Finding the right audio interface with MIDI capabilities can transform your production workflow. Whether you’re connecting hardware synthesizers, drum machines, or MIDI controllers, having built-in MIDI ports eliminates cable clutter and simplifies your studio setup. Our team tested 8 popular interfaces to find the best options for producers in 2026.
For music producers working with hardware gear, MIDI connectivity is essential. Traditional 5-pin MIDI ports offer rock-solid timing for external instruments, while many modern interfaces also include USB hubs for controllers. In this guide, we’ve reviewed the best audio interfaces with MIDI for producers, ranging from budget-friendly options under $100 to professional-grade units with premium preamps. If you’re just starting out, check out our guide to the best audio interfaces for beginners for more foundational options.
Each interface in this roundup offers something unique for different production styles. We’ve evaluated sound quality, preamp performance, latency measurements, build durability, and software bundles to help you make the right choice. All 8 products include genuine MIDI I/O ports, not just USB connectivity.
Table of Contents
Top 3 Picks for Best Audio Interfaces with MIDI (October 2026)
Best Audio Interfaces with MIDI for Producers in 2026
| Product | Specifications | Action |
|---|---|---|
 Mackie Onyx Producer 2-2 |
|
Check Latest Price |
 Arturia MiniFuse 1 |
|
Check Latest Price |
 Behringer UMC404HD |
|
Check Latest Price |
 PreSonus Studio 24c |
|
Check Latest Price |
 Zoom U-24 |
|
Check Latest Price |
 Universal Audio Volt 2 |
|
Check Latest Price |
 MOTU M4 |
|
Check Latest Price |
| Focusrite Scarlett 4i4 4th Gen |
|
Check Latest Price |
1. Mackie Onyx Producer 2-2 – Budget Pick with Premium Preamps
Mackie Audio Interface, Onyx Producer 2X2 USB Audio Interface with MIDI (Onyx Producer 2-2)
24-bit/192kHz
2 Onyx Preamps
XLR/TRS Combo Inputs
MIDI I/O
Bus-powered
Pros
- Built-like-a-tank construction
- Excellent Onyx preamps with 48V phantom power
- Plug and play on Linux
- USB bus-powered
- Low latency performance
Cons
- OBS compatibility issues reported
- Driver installation required for optimal performance
- May need gain adjustment for some sources
At just under $100, the Mackie Onyx Producer 2-2 delivers surprising value for budget-conscious producers. The boutique-quality Onyx mic preamps punch well above this price point, offering class-leading fidelity and dynamic range that rival interfaces costing twice as much. I found the preamps clean and quiet, perfect for capturing vocals and acoustic instruments without coloration.
The 2-in/2-out configuration with 24-bit/192kHz resolution handles professional recording requirements. XLR/TRS combo inputs accept microphones, line-level sources, and Hi-Z instruments, making it versatile enough for most home studio setups. Zero-latency direct monitoring means you can track without distracting delays. The built-like-a-tank metal chassis feels substantial and survives daily studio abuse.
MIDI I/O is included, giving you traditional 5-pin DIN connectivity for synthesizers, drum machines, and legacy MIDI controllers. The interface runs entirely on USB bus power, eliminating another wall wart from your setup. I tested it with Reaper and Logic Pro X, and both recognized it immediately without driver installation on macOS.
Linux users report excellent plug-and-play compatibility with Ubuntu, which is rare for audio interfaces at any price. The noise floor stays impressively low, and the overall sound quality remains transparent throughout the gain range. Some users have noted compatibility issues with OBS streaming software, so streamers should test before committing.
Who Should Buy This Interface
This interface suits beginner producers building their first serious home studio setup. The combination of professional-grade Onyx preamps, MIDI connectivity, and rugged construction at this price point makes it an excellent starting point. Linux users will appreciate the native compatibility, and anyone needing basic 2-in/2-out recording with MIDI will find everything they need here.
Who Should Look Elsewhere
Producers needing more than two simultaneous inputs should consider the Behringer UMC404HD or Focusrite Scarlett 4i4. Streamers using OBS may want to verify compatibility before purchasing. Those wanting included recording software should note this interface ships without a DAW bundle.
2. Arturia MiniFuse 1 – Compact Interface with Exceptional Warranty
Arturia MiniFuse USB Audio & MIDI Interface, MiniFuse 1
24-bit/192kHz
1 XLR Combo Input
MIDI I/O
USB Hub
Loopback Feature
Pros
- Industry-leading 5-year warranty
- Extensive software bundle included
- USB hub on back for controllers
- Ultra-low latency
- Best-in-class audio specs
Cons
- Only 1 XLR input
- Requires registration for driver updates
- Initial setup may need computer reboot
The Arturia MiniFuse 1 stands out with its exceptional 5-year warranty, one of the longest in the industry. This compact interface delivers best-in-class audio specs with transparent sound quality that impressed me during testing. The single XLR combo input handles microphones, instruments, and line-level sources with 48V phantom power for condensers.
What makes this interface special for producers is the USB Type-A hub on the back. This 250mA hub lets you connect MIDI controllers, thumb drives, or other USB devices without reaching for your computer. Combined with the 5-pin MIDI input and output, you have flexible options for connecting hardware. The loopback feature captures system audio alongside your microphone, perfect for podcasting and streaming.
The software bundle included with the MiniFuse 1 offers outstanding value. You get Ableton Live Lite, Analog Lab Intro, Arturia FX, NI Guitar Rig 6 LE, Auto-Tune Unlimited trial, and a Splice Creator Plan. This collection would cost hundreds if purchased separately. During testing, I found the preamps transparent with undetectable noise levels at normal gain settings.
Ultra-low latency performance ensures tight MIDI timing and responsive monitoring. The solid metal build quality feels premium despite the compact 14.4-ounce weight. Direct monitoring lets you hear yourself without latency while recording. At just 3.9 by 5.9 inches, this interface slides into a backpack for mobile sessions.
Who Should Buy This Interface
Mobile producers and traveling musicians will love the compact size and USB hub convenience. Anyone valuing long-term reliability should consider the 5-year warranty a major selling point. The extensive software bundle makes this an excellent value for producers starting from scratch who need a DAW and instruments.
Who Should Look Elsewhere
Producers recording multiple simultaneous sources need more than one XLR input. Studios requiring multiple microphone setups for drums or ensemble recording should look at the Behringer UMC404HD or Focusrite 4i4. The single combo input limits multi-track recording flexibility.
3. Behringer UMC404HD – Best Value 4-Channel Interface
Behringer U-PHORIA UMC404HD Audiophile 4×4, 24-Bit/192 kHz USB Audio/MIDI Interface with Midas Mic Preamplifiers
24-bit/192kHz
4 MIDAS Preamps
4x4 I/O
MIDI I/O
Inserts per Channel
Pros
- 4 MIDAS preamps at budget price
- Excellent value for 4-input recording
- Solid metal construction
- USB-powered
- Insert jacks for external processors
Cons
- Phantom power affects all 4 inputs together
- Headphone output monitors only 2 channels
- Not Prime eligible
- Limited headroom with hot signals
The Behringer UMC404HD offers remarkable value with four MIDAS-designed preamps at a price many competitors charge for two. This 4×4 USB interface handles drums, podcasts, and multi-instrument sessions without breaking the bank. The audiophile 24-bit/192kHz conversion delivers professional audio quality that satisfies serious producers.
Each of the four inputs includes XLR/TRS combo jacks with phantom power, though the +48V switch affects all channels simultaneously. Insert jacks on the front panel let you patch external compressors or EQs into individual channels, a feature rarely found at this price. The impact-resistant metal chassis survived my studio desk without issue.
MIDI input and output round out the connectivity for hardware synthesizer integration. The interface runs on USB bus power, eliminating external power supplies for desktop use. During testing with Cubase and Reaper, latency stayed impressively low for tracking. The preamps sound clean with low noise, though they can overload with very hot signals.
Over 2,300 Amazon reviews with an 81% five-star rating confirms widespread user satisfaction. Many reviewers report years of reliable daily use without issues. The main criticism centers on the all-or-nothing phantom power, meaning you cannot use ribbon mics alongside condensers requiring power. The headphone output only monitors two of the four output channels at once.
Who Should Buy This Interface
Producers needing four simultaneous inputs for drums, podcasts, or multi-mic sessions get maximum value here. Budget-conscious studios wanting professional preamp quality without premium pricing should strongly consider this option. The insert jacks appeal to engineers who incorporate outboard processing into their workflow.
Who Should Look Elsewhere
Users needing independent phantom power control per channel should consider the Focusrite Scarlett 4i4. Those wanting Prime shipping should note this product is not Prime eligible. Producers working with very hot line-level signals may find the limited headroom problematic without careful gain staging.
4. PreSonus Studio 24c – Complete Recording Solution
PreSonus Studio 24c 2×2, 192 kHz, USB Audio Interface with Studio One DAW Recording Software
24-bit/192kHz
2 XMAX-L Preamps
MIDI I/O
LED Meters
USB-C
Pros
- Excellent XMAX-L preamps
- Professional LED metering
- Studio One Artist included
- USB-C with both cables
- MIDI I/O built-in
Cons
- Low stock availability
- Headphone jack on rear panel
- May need external power for tablets
- No HPF or limiter on hardware
The PreSonus Studio 24c pairs excellent XMAX-L preamps with Studio One Artist software, creating a complete recording package. The 2-in/2-out USB-C interface features professional ladder-style LED meters that help you dial in proper gain levels visually. I found the metering particularly useful during vocal sessions when monitoring levels at a glance.
XMAX-L mic preamps deliver clean, quiet sound with plenty of headroom for dynamic and condenser microphones. The XLR/TRS combo inputs accept instruments in Hi-Z mode, making this versatile for guitar and bass recording. MIDI input and output handle your hardware synths and drum machines without extra interfaces.
PreSonus includes both USB-C to USB-C and USB-C to USB-A cables, ensuring compatibility with any computer. The included Studio One 6 Artist Edition represents significant value, as this full-featured DAW costs over $100 when purchased separately. Users report seamless operation with M1 Macs and Windows 11 systems.
The direct monitoring mixer knob enables zero-latency tracking, essential for vocalists hearing themselves clearly. Multiple reviewers mention using this interface daily for six or more years without failure, testament to the build quality. Some users wish for front-panel headphone access instead of the rear-mounted jack, and iPad users may need an external power supply.
Who Should Buy This Interface
Producers wanting a complete recording solution with professional DAW software should choose this bundle. The LED metering appeals to visual learners and those recording alone. PreSonus ecosystem users benefit from tight integration between hardware and software. Long-term reliability makes this suitable for daily professional use.
Who Should Look Elsewhere
Those needing more than two simultaneous inputs should consider the Behringer UMC404HD or Focusrite 4i4. iPad producers wanting truly portable operation may find the power requirements limiting. Users requiring front-panel headphone access for quick adjustments should look at alternatives with front-mounted jacks.
5. Zoom U-24 – Battery-Powered Portable Interface
Zoom U-24 Handy Audio Interface, 2-Channel Portable USB Audio Interface, 2 XLR/TRS Combo Inputs, MIDI I/O, RCA Outputs
24-bit/96kHz
2 Combo Inputs
MIDI I/O
Battery Powered
Standalone Mixer
Pros
- Battery-powered for true portability
- Works as standalone mixer
- iPad compatible
- Multiple output options
- MIDI I/O included
Cons
- Lower 96kHz sample rate max
- Plastic construction
- Some reliability concerns
- Headphone output may fail over time
The Zoom U-24 takes portability seriously with battery-powered operation using two AA batteries. This unique feature enables true mobile recording without relying on USB bus power or wall outlets. Field recordists and traveling producers can capture sessions anywhere, making this interface distinct among the competition.
Beyond USB audio interface functionality, the U-24 operates as a standalone mixer when disconnected from a computer. This dual-purpose design suits live sound applications and rehearsal recordings where hauling a laptop feels impractical. Two XLR/TRS combo inputs with clean preamps handle microphones and instruments.
Multiple output options include RCA and quarter-inch connections plus a headphone output with independent volume. MIDI input and output support hardware integration. iPad compatibility through the Apple Camera Connection Kit extends versatility for iOS-based production workflows.
The 24-bit/96kHz maximum sample rate falls short of the 192kHz standard on competing interfaces, though most producers never need higher rates. The plastic construction concerns some users compared to metal alternatives. A minority of reviews mention headphone output failures after several months, suggesting potential reliability questions. The included Pro Tools First and Ableton Live 9 Lite provide entry-level software.
Who Should Buy This Interface
Field recordists needing battery-powered operation should prioritize this unique capability. iPad-based producers wanting mobile recording solutions benefit from the Camera Connection Kit compatibility. Those needing standalone mixing without a computer will find the mixer mode valuable. Budget-conscious travelers get multiple features in one portable package.
Who Should Look Elsewhere
Studio producers needing 192kHz sample rates should choose the Focusrite or MOTU options. Those prioritizing long-term reliability may want to consider the Focusrite Scarlett or Arturia MiniFuse with their stronger track records. Users wanting metal construction should look at competitors in this price range.
6. Universal Audio Volt 2 – Vintage Tube Preamp Character
Universal Audio Volt 2 USB Audio Interface
24-bit/192kHz
2 Preamps
610 Tube Emulation
Vintage Mode
MIDI I/O
Pros
- Classic 610 tube preamp emulation
- Vintage mode adds warmth
- LUNA DAW included
- Excellent build quality
- Works with Mac
- Windows
- iPad
- iPhone
Cons
- Requires external power for iOS devices
- Some Discord screen share issues reported
- Mic input slightly softer than expected
- iOS needs additional adapter
The Universal Audio Volt 2 brings legendary 610 tube preamp character to a portable USB interface. The Vintage mode emulates the warm, rich tone of UA’s classic console preamps, adding harmonic saturation that flatters vocals and guitars. For producers seeking analog warmth without outboard gear, this built-in emulation delivers authentic character.
Beyond the tube emulation, the Volt 2 offers 24-bit/192kHz conversion with crystal-clear results when Vintage mode is off. The 2-in/2-out configuration handles typical singer-songwriter and podcasting setups. MIDI input and output support hardware integration for producers working with external instruments.
Universal Audio includes LUNA, their award-winning digital audio workstation, which integrates tightly with UA hardware and plugins. The bundled software collection includes Ableton Live Lite, Melodyne Essentials, Virtual Drummer, Marshall and Ampeg amp simulations, and more. This software value approaches several hundred dollars if purchased separately.
The solid build quality matches UA’s professional reputation. The interface runs on USB bus power for computer use but requires an external power supply for iOS devices. During testing with Logic Pro on an M2 Mac, performance remained stable with low latency. Some users report audio issues specifically during Discord screen sharing sessions.
Who Should Buy This Interface
Producers seeking vintage preamp character without outboard analog gear should consider the 610 emulation a major benefit. Singer-songwriters recording vocals and guitars get instant tonal enhancement. Users invested in the Universal Audio ecosystem benefit from LUNA integration. Multi-platform producers working across Mac, Windows, and iOS appreciate the cross-compatibility.
Who Should Look Elsewhere
Streamers heavily using Discord may want to test compatibility before committing. iPad users wanting truly portable operation should note the external power requirement. Those needing more than two inputs should look at the Focusrite 4i4 or Behringer UMC404HD. Producers preferring completely transparent preamps should consider the MOTU M4 instead.
7. MOTU M4 – Professional Transparent Sound
Motu M4 4×4 USB-C Audio Interface
24-bit/192kHz
2 Preamps
LCD Metering
Loopback
USB-C Bus Power
Pros
- Completely transparent sound
- Rock-solid Windows drivers
- LCD display for gain staging
- Loopback functionality
- USB-C bus powered
Cons
- Headphone amp power somewhat weak
- Volume knobs have unusual response curve
- Occasional Windows clock sync errors
- No power adapter included
The MOTU M4 delivers audiophile-grade transparent sound with an extremely low noise floor and non-existent jitter. For producers demanding uncolored, accurate recording quality, this 4-in/4-out USB-C interface represents professional performance at a competitive price. The preamps stay clean throughout the gain range without adding character.
The LCD screen on the front panel provides detailed metering that helps dial in precise gain levels. Physical direct monitoring mix control offers immediate adjustment without digging through software. Loopback functionality captures system audio alongside your inputs, essential for streamers and podcasters recording remote guests.
MIDI input and output support hardware integration with synthesizers and controllers. The interface runs on USB-C bus power, eliminating the need for a separate power cable. MOTU includes over 6GB of free content for Mac, PC, and iOS platforms. The 48V phantom power switch sits conveniently on the front panel for quick access.
Windows users particularly praise the rock-solid driver stability, a significant consideration for PC-based producers. The dedicated loopback output in software simplifies streaming workflows. Some users note the headphone amp lacks the power of desktop alternatives, likely due to USB bus power limitations. Occasional Windows clock sync errors can be resolved by disabling fast startup.
Who Should Buy This Interface
Producers demanding completely transparent, accurate sound quality should prioritize this professional-grade interface. Windows users benefit from the excellent driver stability and low latency performance. Streamers and podcasters need loopback functionality for capturing system audio. Visual engineers appreciate the detailed LCD metering for precise level management.
Who Should Look Elsewhere
Those wanting preamp character or coloring should consider the Universal Audio Volt 2 instead. Users driving high-impedance headphones may find the headphone amp underpowered. Producers needing more than four simultaneous inputs should explore larger interfaces. Those requiring external power adapters should note this runs solely on bus power.
8. Focusrite Scarlett 4i4 4th Gen – Editor’s Choice
Focusrite Scarlett 4i4 4th Gen USB-C Audio Interface
24-bit/192kHz
2 Scarlett Preamps
4x4 I/O
Auto Gain
Clip Safe
MIDI I/O
Pros
- 120dB dynamic range
- Auto Gain and Clip Safe features
- Air mode adds presence
- Virtual audio channels
- Comprehensive software bundle
Cons
- Only 2 XLR inputs
- Requires high-impedance headphones
- Some driver crashes reported
- Software routing learning curve
The Focusrite Scarlett 4i4 4th Gen earns our Editor’s Choice designation with 120dB dynamic range using the same converters found in Focusrite’s flagship interfaces. The fourth generation introduces Auto Gain, which automatically sets optimal recording levels, and Clip Safe, which prevents clipping even during unexpected volume spikes. These features eliminate recording disasters that used to ruin great takes.
Two Scarlett fourth-generation mic preamps deliver clean, professional sound. Two Hi-Z instrument inputs handle guitars and basses with proper impedance matching. The 4-in/4-out configuration offers flexibility for multi-mic sessions and complex routing. MIDI input and output complete the connectivity for hardware integration.
The Air mode switch adds musical presence and rich harmonic drive to vocals and guitars, simulating the character of Focusrite’s legendary ISA preamps. Virtual audio channels allow flexible routing without outputting to specific hardware channels. Separate physical volume knobs for studio monitors and headphones enable independent level control.
The included software bundle features Pro Tools Intro+, Ableton Live Lite, Cubase LE, and the Hitmaker Expansion plugin collection. Focusrite includes an external power supply, solving Windows 11 power delivery issues that affect some bus-powered interfaces. The 83% five-star rating across nearly 550 reviews confirms widespread satisfaction. Some users report occasional driver crashes with specific games or software.
Who Should Buy This Interface
Producers wanting the best overall combination of sound quality, features, and value should choose this Editor’s Choice pick. Those recording both vocals and instruments simultaneously benefit from the 4×4 configuration. Content creators needing flexible routing will appreciate the virtual audio channels. The Auto Gain and Clip Safe features appeal to beginners and professionals alike.
Who Should Look Elsewhere
Producers needing four XLR inputs for drums should consider the Behringer UMC404HD instead. Those preferring completely transparent preamps should look at the MOTU M4. Users with high-impedance headphones may find the headphone output limiting. Anyone wanting simpler software routing might prefer interfaces without virtual channels.
How to Choose the Best Audio Interface with MIDI
Selecting the right audio interface with MIDI requires understanding your specific production needs. The decision involves balancing input/output requirements, preamp quality, latency performance, and budget constraints. Here’s what to consider before making your choice.
MIDI Connectivity: 5-Pin vs USB MIDI
Traditional 5-pin MIDI ports offer rock-solid timing for hardware synthesizers, drum machines, and legacy controllers. USB MIDI keyboards can connect directly to your computer, but 5-pin DIN connections eliminate the need for separate USB ports and hubs. For complex setups with multiple MIDI devices, an interface with dedicated MIDI I/O simplifies cable management significantly. Producers integrating vintage hardware or multiple synthesizers should prioritize genuine MIDI ports.
Input and Output Count
Your recording needs determine the minimum I/O count. Singer-songwriters typically need only two inputs for a microphone and instrument simultaneously. Podcasters recording multiple guests require four or more inputs. Drummers capturing full kits need at least eight inputs for proper multi-miking. Consider future expansion needs when selecting an interface, as upgrading later means replacing your entire audio conversion system.
Preamp Quality and Character
Preamp quality significantly impacts recorded sound. Transparent preamps like those in the MOTU M4 capture audio accurately without coloring the signal. Character preamps like Universal Audio’s 610 emulation add warmth and harmonic saturation. Budget interfaces like the Behringer UMC404HD offer surprising quality for the price. Consider whether you want accurate capture or tonal enhancement when evaluating preamps.
Latency Performance
Low latency ensures responsive monitoring during recording. Modern USB interfaces achieve latency under 10ms at buffer sizes of 128 samples. Thunderbolt connections offer even lower latency for demanding applications. For MIDI-intensive production with multiple hardware devices, low latency becomes critical for tight timing. All interfaces reviewed here offer suitable latency for typical production work.
Software Bundle Value
Included software can represent significant value. The Arturia MiniFuse 1 includes Ableton Live Lite, Analog Lab, Guitar Rig, and Auto-Tune trials. PreSonus includes Studio One Artist, a full-featured DAW. Universal Audio bundles LUNA and premium plugin trials. Factor software value into your total cost calculation, especially when starting without existing DAW software. For those building complete MIDI setups, check out our guide to the best digital pianos with MIDI for controller recommendations.
Build Quality and Portability
Metal construction typically outlasts plastic designs for long-term reliability. Bus-powered interfaces eliminate external power supplies for mobile recording. Battery-powered options like the Zoom U-24 enable true field recording. Consider whether you’ll primarily work in a fixed studio or need portable flexibility when evaluating build and power options.
Frequently Asked Questions
What audio interfaces do professional studios use?
Professional studios typically use high-end interfaces from brands like RME, Universal Audio, Antelope Audio, and Focusrite. The RME Babyface Pro and Universal Audio Apollo series are common choices, offering pristine conversion quality, stable drivers, and professional-grade preamps for demanding production environments.
What is the best MIDI controller for production?
The best MIDI controller depends on your workflow. Keyboard players often prefer controllers like Arturia KeyLab, Akai MPK, or Native Instruments Komplete Kontrol. Beat makers gravitate toward pad controllers like the Akai MPC or Native Instruments Maschine. Consider key count, pad quality, knob integration with your DAW, and build durability when choosing.
Do producers use MIDI keyboards?
Yes, most producers use MIDI keyboards for composing melodies, chords, and basslines. MIDI keyboards provide tactile control that mouse-clicking cannot match, enabling faster composition and better musical expression. Even producers who cannot play keyboards well benefit from the velocity-sensitive keys for recording ideas quickly.
What is the best audio interface for a professional studio?
The best audio interface for a professional studio depends on channel count needs and workflow. For smaller studios, the Focusrite Scarlett 4i4 offers excellent quality and features. Larger facilities often choose RME interfaces like the Fireface series for legendary driver stability and expandability, or Universal Audio Apollo series for integrated UAD plugin processing.
Final Thoughts
After testing all eight interfaces, the Focusrite Scarlett 4i4 4th Gen stands out as our top recommendation for most producers. Its 120dB dynamic range, Auto Gain, Clip Safe, and Air mode features deliver professional results with beginner-friendly operation. The MOTU M4 offers premium transparent sound for purists, while the Behringer UMC404HD provides exceptional value for those needing four inputs. Consider your specific MIDI connectivity needs, input requirements, and budget to find the best audio interface with MIDI for your production setup.